The average salary for an informatics nurse specialist in South Carolina is around $98,280 per year.
Avg Salary
Informatics nurse specialists earn an average yearly salary of $98,280.
Wages typically start from $58,000 and go up to $148,660.
53% above national average Updated in 2025
Informatics nurse specialist earnings by seniority
Top-level informatics nurse specialist earnings begin at:
$71.47 per hour
$148,660 per year
Senior-level informatics nurse specialist earnings begin at:
$58.93 per hour
$122,570 per year
Mid-level informatics nurse specialist earnings begin at:
$47.25 per hour
$98,280 per year
Junior-level informatics nurse specialist earnings begin at:
$36.57 per hour
$76,070 per year
Starting level informatics nurse specialist earnings begin at:
$27.89 per hour
$58,000 per year
Approximate values based on highest and lowest earning segments.
Informatics nurse specialist salary by state
| State Name | Average Salary |
|---|---|
| South Dakota | $99,790 |
| Vermont | $99,610 |
| Indiana | $98,810 |
| Utah | $98,770 |
| Pennsylvania | $98,550 |
| South Carolina | $98,280 |
| New Mexico | $98,220 |
| Oklahoma | $95,930 |
| Iowa | $95,920 |
| Maine | $95,820 |
| Louisiana | $95,660 |
| Tennessee | $95,630 |
| Kentucky | $95,090 |
| Missouri | $92,060 |
| Nebraska | $91,810 |
| Montana | $91,310 |
| Hawaii | $88,640 |
| Alaska | $88,520 |
| Mississippi | $86,280 |
| Arkansas | $81,760 |
| Idaho | $75,310 |
| West Virginia | $72,680 |
| Guam | $50,090 |
| Virgin Islands, U.S. | $49,940 |
| Puerto Rico | $44,090 |
| Rhode Island | $134,630 |
| Washington | $129,410 |
| Massachusetts | $128,240 |
| Colorado | $127,750 |
| California | $127,720 |
| New Jersey | $122,890 |
| Oregon | $121,620 |
| Virginia | $120,840 |
| District of Columbia | $116,820 |
| Maryland | $113,610 |
| Delaware | $110,560 |
| Wyoming | $109,780 |
| New York | $109,610 |
| Connecticut | $109,600 |
| New Hampshire | $107,670 |
| Texas | $107,390 |
| North Carolina | $106,850 |
| Minnesota | $106,350 |
| Georgia | $106,240 |
| North Dakota | $105,470 |
| Nevada | $104,060 |
| Arizona | $103,530 |
| Michigan | $103,410 |
| Ohio | $102,320 |
| Florida | $101,900 |
| Alabama | $101,770 |
| Illinois | $101,570 |
| Kansas | $100,770 |
| Wisconsin | $100,440 |
How do informatics nurse specialist salaries compare to similar careers?
Informatics nurse specialists earn about the same as related careers in South Carolina. On average, they make less than physician assistants but more than bioinformatics scientists.
| Career | Median Salary |
|---|---|
| Physician assistant salary | $122K |
| Photonics engineer salary | $110K |
| Information security analyst salary | $106K |
| Electrical engineer salary | $98K |
| Computer systems administrator salary | $93K |
| Computer systems analyst salary | $98K |
| Informatics nurse specialist salary | $98K |
| Computer programmer salary | $100K |
| Radiation therapist salary | $101K |
| Bioinformatics scientist salary | $92K |
Source: CareerExplorer (Aggregated)